Non-rash skin toxicities associated with novel targeted therapies.

  title={Non-rash skin toxicities associated with novel targeted therapies.},
  author={Mario E. Lacouture and Scott A. Boerner and Patricia M. LoRusso},
  journal={Clinical lung cancer},
  volume={8 Suppl 1},
Many novel targeted agents have emerged against a variety of malignancies. Although papulopustular rash is the most commonly observed side effect associated with many of these agents, several non-rash skin toxicities have been identified that frequently result in the delay or discontinuation of anticancer therapy. These toxicities include skin hyperpigmentation, xerosis, pruritus, hair growth and color abnormalities, periungual and nail alterations, and hand-foot skin reaction. It is important… CONTINUE READING
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