Non-random distribution of homo-repeats: links with biological functions and human diseases

Abstract

The biological function of multiple repetitions of single amino acids, or homo-repeats, is largely unknown, but their occurrence in proteins has been associated with more than 20 hereditary diseases. Analysing 122 bacterial and eukaryotic genomes, we observed that the number of proteins containing homo-repeats is significantly larger than expected from… (More)
DOI: 10.1038/srep26941

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