Non-pumped sodium fluxes in human red blood cells. Evidence for facilitated diffusion.

@article{Beaug1975NonpumpedSF,
  title={Non-pumped sodium fluxes in human red blood cells. Evidence for facilitated diffusion.},
  author={Luis A Beaug{\'e}},
  journal={Biochimica et biophysica acta},
  year={1975},
  volume={401 1},
  pages={95-108}
}
Unidirectional and net Na+ fluxes modified by changes in internal Na+ concentration ([Na+]i) were studied in human red blood cells incubated in K+-free solutions containing 10-minus 4 m ouabain. An increase in [Na+]i brought about (a) a reduction in net Na+ gain, (b) no change in Na+ influx, (c) a reduction in the rate constant for Na+ effux and (d) an increase in Na+ efflux. Similar reductions in net Na+ gain were observed when the changes in [Na+]i were carried out at constant [K+]i. In… CONTINUE READING