Non-proteolytic protein ubiquitination is crucial for iron deficiency signaling.

Abstract

Ubiquitination generally targets proteins for recognition and degradation via the 26S proteasome. Activated ubiquitin (E1) is transferred to an ubiquitin conjugase (UBC, E2) which associates with a ubiquitin ligase (E3), and multiple ubiquitin molecules are attached via linkage of Lys 48. By contrast, Lys 63-linked ubiquitin chains modify proteins in a non… (More)
DOI: 10.4161/psb.11424

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