Non-peptide vasopressin V1b receptor antagonists as potential drugs for the treatment of stress-related disorders.

@article{Griebel2005NonpeptideVV,
  title={Non-peptide vasopressin V1b receptor antagonists as potential drugs for the treatment of stress-related disorders.},
  author={Guy Griebel and Jeanne Stemmelin and Claudine Serradeil-Le Gal and Philippe Soubri{\'e}},
  journal={Current pharmaceutical design},
  year={2005},
  volume={11 12},
  pages={
          1549-59
        }
}
Since vasopressin has been shown to be critical for adaptation of the hypothalamo-pituitary-adrenal axis during stress through its ability to potentiate the stimulatory effect of CRF, it has been hypothesized that this peptide may provide a good opportunity for pharmacological treatment of stress-related disorders. The availability of the first orally… CONTINUE READING