Non-opsonic phagocytosis of homologous non-toxigenic and toxigenic Corynebacterium diphtheriae strains by human U-937 macrophages.

@article{Santos2010NonopsonicPO,
  title={Non-opsonic phagocytosis of homologous non-toxigenic and toxigenic Corynebacterium diphtheriae strains by human U-937 macrophages.},
  author={C{\'i}ntia Silva dos Santos and Louisy Sanches dos Santos and M{\^o}nica Cristina de Souza and Fernanda dos Santos Dourado and Alexandre Alves de Souza de Oliveira Dias and Priscila Soares Sabbadini and Gabriela Andrade Pereira and Maulori Curi{\'e} Cabral and Raphael Hirata J{\'u}nior and Ana Lu{\'i}za de Mattos-Guaraldi},
  journal={Microbiology and immunology},
  year={2010},
  volume={54 1},
  pages={
          1-10
        }
}
As interactions between bacteria and macrophages dictate the outcome of most infectious diseases, analyses of molecular mechanisms of non-opsonic phagocytosis should lead to new approaches for the prevention of diphtheria and systemic Corynebacterium diphtheriae infections. The present study aimed to evaluate human macrophage-bacteria interactions in the absence of opsonin antibodies and the influence of the tox gene on this process. Homologous C. diphtheriae tox+ and tox- strains were… CONTINUE READING
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