Non-ohmic proton conductance of mitochondria and liposomes.

  title={Non-ohmic proton conductance of mitochondria and liposomes.},
  author={Guruswamy Krishnamoorthy and Peter C. Hinkle},
  volume={23 8},
Direct measurements of the proton/hydroxyl ion flux across rat liver mitochondria and liposome membranes are reported. H+/OH- fluxes driven by membrane potential (delta psi) showed nonlinear dependence on delta psi both in mitochondria and in liposomes whereas delta pH-driven H+/OH- flux shows linear dependence on delta pH in liposomes. In the presence of low concentrations of a protonophore the H+/OH- flux was linearly dependent on delta psi and showed complex dependence on delta pH. The… CONTINUE READING

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