Non-muscle myosin II in disease: mechanisms and therapeutic opportunities

Abstract

The actin motor protein non-muscle myosin II (NMII) acts as a master regulator of cell morphology, with a role in several essential cellular processes, including cell migration and post-synaptic dendritic spine plasticity in neurons. NMII also generates forces that alter biochemical signaling, by driving changes in interactions between actin-associated… (More)
DOI: 10.1242/dmm.022103

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Cite this paper

@inproceedings{NewellLitwa2015NonmuscleMI, title={Non-muscle myosin II in disease: mechanisms and therapeutic opportunities}, author={Karen A. Newell-Litwa and Rick Horwitz and Marcelo Lazzaron Lamers}, booktitle={Disease models & mechanisms}, year={2015} }