Non-mammalian c-integrases are encoded by giant transposable elements.

  title={Non-mammalian c-integrases are encoded by giant transposable elements.},
  author={C{\'e}dric Feschotte and Ellen J. Pritham},
  journal={Trends in genetics : TIG},
  volume={21 10},
In a recent report in Trends in Genetics, Gao and Voytas [1] described a new family of integrase genes that were identified in diverse eukaryotic species, including slime mold, Caenorhabditis elegans, C. briggsae, zebrafish, Takifugu rubripes, Xiphophorus maculates, cow, dog and humans. These genes potentially encode proteins containing w400 amino acids with homology to retroviral integrases and transposases, including the integrase-like proteins encoded by Tlr, a family of atypical mobile… CONTINUE READING
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