Non-linearities in the blood-oxygenation-level dependent (BOLD) response measured by functional magnetic resonance imaging (fMRI)

@article{Huettel2004NonlinearitiesIT,
  title={Non-linearities in the blood-oxygenation-level dependent (BOLD) response measured by functional magnetic resonance imaging (fMRI)},
  author={S. A. Huettel},
  journal={The 26th Annual International Conference of the IEEE Engineering in Medicine and Biology Society},
  year={2004},
  volume={2},
  pages={4413-4416}
}
  • S. A. Huettel
  • Published 2004 in
    The 26th Annual International Conference of the…
A central question in the analysis of functional magnetic resonance imaging (IMRI) data is whether the measured fMRI signal summates in a linear fashion over repeated inputs. Most fMRI studies collect images sensitive to blood-oxygenation-level dependent (BOLD) contrast, which measures the local amount of deoxygenated hemoglobin (dHb). When neurons are active, more oxygenated hemoglobin is supplied than is needed for their metabolic demands, resulting in a decrease in dHb and an increase in MR… CONTINUE READING

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