Non-invasive optical spectroscopy and imaging of human brain function
@article{Villringer1997NoninvasiveOS, title={Non-invasive optical spectroscopy and imaging of human brain function}, author={A. Villringer and B. Chance}, journal={Trends in Neurosciences}, year={1997}, volume={20}, pages={435-442} }
Brain activity is associated with changes in optical properties of brain tissue. Optical measurements during brain activation can assess haemoglobin oxygenation, cytochrome-c-oxidase redox state, and two types of changes in light scattering reflecting either membrane potential (fast signal) or cell swelling (slow signal), respectively. In previous studies of exposed brain tissue, optical imaging of brain activity has been achieved at high temporal and microscopical spatial resolution. Now… Expand
Paper Mentions
Observational Clinical Trial
In this study the investigator would like to examine hemodynamic cerebral blood flow and
brain function by the use of Invos cerebral oximetry in women undergoing cesarean section… Expand
Conditions | Anoxia |
---|---|
Intervention | Device |
Observational Clinical Trial
The investigators plan to use optical brain imaging technology to observe patients with
current major depression before, during, and after repetitive Transcranial Magnetic… Expand
Conditions | Major Depression |
---|---|
Intervention | Device |
Observational Clinical Trial
Background:
- Non-invasive functional near infrared (fNIR) imaging techniques use infrared light to
detect changes in blood volume and oxygen levels during brain activity. fNIR is… Expand
Conditions | Cognitive Function |
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- 2013
- 30
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References
SHOWING 1-10 OF 84 REFERENCES
Simultaneous Recording of Cerebral Blood Oxygenation Changes during Human Brain Activation by Magnetic Resonance Imaging and Near-Infrared Spectroscopy
- Chemistry, Medicine
- Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism
- 1996
- 447
Coupling of brain activity and cerebral blood flow: basis of functional neuroimaging.
- Computer Science, Medicine
- Cerebrovascular and brain metabolism reviews
- 1995
- 579
Dynamic multichannel near-infrared optical imaging of human brain activity.
- Materials Science, Medicine
- Journal of applied physiology
- 1993
- 341
- PDF
Optical imaging of epileptiform and functional activity in human cerebral cortex
- Chemistry, Medicine
- Nature
- 1992
- 330
Noninvasive cerebral optical spectroscopy for monitoring cerebral oxygen delivery and hemodynamics
- Medicine
- Critical care medicine
- 1991
- 321
Functional architecture of cortex revealed by optical imaging of intrinsic signals
- Materials Science, Medicine
- Nature
- 1986
- 1,205
- PDF
Real-time optical imaging of naturally evoked electrical activity in intact frog brain
- Biology, Medicine
- Nature
- 1984
- 160
Near infrared spectroscopy (NIRS): A new tool to study hemodynamic changes during activation of brain function in human adults
- Chemistry, Medicine
- Neuroscience Letters
- 1993
- 962
Assessment of local brain activation. A simultaneous PET and near-infrared spectroscopy study.
- Materials Science, Medicine
- Advances in experimental medicine and biology
- 1997
- 148
Spatial and temporal analysis of human motor activity using noninvasive NIR topography.
- Chemistry, Medicine
- Medical physics
- 1995
- 619