Non-invasive optical spectroscopy and imaging of human brain function

@article{Villringer1997NoninvasiveOS,
  title={Non-invasive optical spectroscopy and imaging of human brain function},
  author={A. Villringer and B. Chance},
  journal={Trends in Neurosciences},
  year={1997},
  volume={20},
  pages={435-442}
}
Brain activity is associated with changes in optical properties of brain tissue. Optical measurements during brain activation can assess haemoglobin oxygenation, cytochrome-c-oxidase redox state, and two types of changes in light scattering reflecting either membrane potential (fast signal) or cell swelling (slow signal), respectively. In previous studies of exposed brain tissue, optical imaging of brain activity has been achieved at high temporal and microscopical spatial resolution. Now… Expand
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