Non-invasive liver iron quantification by SQUID-biosusceptometry and serum ferritin iron as new diagnostic parameters in hereditary hemochromatosis.

@article{Nielsen2002NoninvasiveLI,
  title={Non-invasive liver iron quantification by SQUID-biosusceptometry and serum ferritin iron as new diagnostic parameters in hereditary hemochromatosis.},
  author={Peter N\ortoft Nielsen and Rainer Engelhardt and Jochen D{\"u}llmann and Roland L. Fischer},
  journal={Blood cells, molecules & diseases},
  year={2002},
  volume={29 3},
  pages={451-8}
}
In the HFE-gene era, precise diagnostic parameters remain important to characterize individual iron stores, because the indication for therapy and prognosis are mainly related to the extent of iron loading. The frequently used serum ferritin interferes with non-iron related factors such as inflammation and may produce falsely positive values. We used a SQUID-biosusceptometer in a large series of patients (n = 679) to measure liver iron concentration in the differential diagnosis and therapy… CONTINUE READING

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