Non-invasive imaging of dendritic cell migration in vivo.

  title={Non-invasive imaging of dendritic cell migration in vivo.},
  author={Dirk Baumjohann and Manfred B Lutz},
  volume={211 6-8},
Dendritic cells (DCs) play important roles in the initiation of adaptive immune responses. The transport of antigen from the infection site to the draining lymph node by DCs is a crucial component in this process. Accordingly, immunotherapeutic applications of in vitro-generated DCs require reliable methods experimentally in mice and clinically in patients to monitor the efficiency of their successful lymph node homing after injection. Recent developments of new methods to follow DC migration… CONTINUE READING
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