Non-invasive exhaled volatile organic biomarker analysis to detect inflammatory bowel disease (IBD).

@article{Arasaradnam2016NoninvasiveEV,
  title={Non-invasive exhaled volatile organic biomarker analysis to detect inflammatory bowel disease (IBD).},
  author={Ramesh P. Arasaradnam and Michael Mcfarlane and Emma Daulton and Jim R Skinner and Nicola O'Connell and Subiatu Wurie and Samantha Chambers and Chuka U. Nwokolo and Karna D. Bardhan and Richard S. Savage and James A. Covington},
  journal={Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver},
  year={2016},
  volume={48 2},
  pages={148-53}
}
INTRODUCTION Early inflammatory bowel disease (IBD) diagnosis remains a clinical challenge. Volatile organic compounds (VOCs) have shown distinct patterns in Crohn's disease (CD) and ulcerative colitis (UC). VOC production, reflecting gut fermentome metabolites, is perturbed in IBD. VOC sampling is non-invasive, with various compounds identified from faecal, breath and urine samples. This study aimed to determine if FAIMS (field asymmetric ion mobility spectroscopy) analysis of exhaled VOCs… CONTINUE READING
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