Non-invasive estimation of hepatic blood perfusion from H2 15O PET images using tissue-derived arterial and portal input functions

@article{Kudomi2008NoninvasiveEO,
  title={Non-invasive estimation of hepatic blood perfusion from H2 15O PET images using tissue-derived arterial and portal input functions},
  author={Nobuyuki Kudomi and Lotfi Slimani and Mikko J. J{\"a}rvisalo and J{\'a}n Ki{\vs}{\vs} and Riikka Lautam{\"a}ki and Gratian A Naum and Timo J A Savunen and Juhani Knuuti and Hidehiro Iida and P. Nuutila and Patricia Iozzo},
  journal={European Journal of Nuclear Medicine and Molecular Imaging},
  year={2008},
  volume={35},
  pages={1899-1911}
}
The liver is perfused through the portal vein and the hepatic artery. When its perfusion is assessed using positron emission tomography (PET) and 15O-labeled water (H2 15O), calculations require a dual blood input function (DIF), i.e., arterial and portal blood activity curves. The former can be generally obtained invasively, but blood withdrawal from the portal vein is not feasible in humans. The aim of the present study was to develop a new technique to estimate quantitative liver perfusion… CONTINUE READING
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Liver kinetics

  • OL Munk, L Bass, K Roelsgaard, D Bender, SB Hansen, S. Keiding
  • 2001
Highly Influential
1 Excerpt

Error analysis

  • H Iida, I Kanno, S Miura, M Murakami, K Takahashi, K Uemura
  • 1986
Highly Influential
1 Excerpt

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