Non-invasive characterization of beta-amyloid(1-40) vasoactivity by functional magnetic resonance imaging in mice.

Abstract

Neurovascular regulation, which is critical to the efficient functioning of the brain, is impaired in Alzheimer's disease and in transgenic mice overexpressing Abeta. Although senile plaques and neurofibrillary tangles represent neuropathological hallmarks of Alzheimer's disease, deposition of Abeta in cerebral blood vessels also likely plays a significant… (More)
DOI: 10.1016/j.neuroscience.2008.04.021

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@article{Luo2008NoninvasiveCO, title={Non-invasive characterization of beta-amyloid(1-40) vasoactivity by functional magnetic resonance imaging in mice.}, author={F. Luo and T. R. Seifert and Rohinton P Edalji and Ralf W Loebbert and Vincent P. Hradil and John E. Harlan and M. Schmidt and Volker Nimmrich and Brian Cox and G. B. Fox}, journal={Neuroscience}, year={2008}, volume={155 1}, pages={263-9} }