Non-invasive assessment of pulse wave velocity in mice by means of ultrasound images.

  title={Non-invasive assessment of pulse wave velocity in mice by means of ultrasound images.},
  author={Nicole Di Lascio and Francesco Stea and Claudia Kusmic and Rosa Sicari and Francesco Faita},
  volume={237 1},
OBJECTIVE Pulse wave velocity (PWV) is considered as a surrogate marker of arterial stiffness and could be useful for characterizing cardiovascular disease progression even in mouse models. Aim of this study was to develop an image process algorithm for assessing arterial PWV in mice using ultrasound images only and test it on the evaluation of age-associated differences in abdominal aorta PWV. METHODS Ultrasound scans were obtained from ten adult (mean age: 5.5 months) and nine old (mean age… CONTINUE READING


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