Non-human primate models for AIDS vaccine research.

  title={Non-human primate models for AIDS vaccine research.},
  author={Shiu-Lok Hu},
  journal={Current drug targets. Infectious disorders},
  volume={5 2},
  • Shiu-Lok Hu
  • Published 2005 in Current drug targets. Infectious disorders
Since the discovery of simian immunodeficiency viruses (SIV) causing AIDS-like diseases in Asian macaques, non-human primates (NHP) have played an important role in AIDS vaccine research. A multitude of vaccines and immunization approaches have been evaluated, including live attenuated viruses, DNA vaccines, viral and bacterial vectors, subunit proteins, and combinations thereof. Depending on the particular vaccine and model used, varying degrees of protection have been achieved, including… CONTINUE READING