Non-homogeneous models of sequence evolution in the Bio++ suite of libraries and programs

@inproceedings{Dutheil2008NonhomogeneousMO,
  title={Non-homogeneous models of sequence evolution in the Bio++ suite of libraries and programs},
  author={Julien Y Dutheil and Bastien Boussau},
  booktitle={BMC Evolutionary Biology},
  year={2008}
}
Accurately modeling the sequence substitution process is required for the correct estimation of evolutionary parameters, be they phylogenetic relationships, substitution rates or ancestral states; it is also crucial to simulate realistic data sets. Such simulation procedures are needed to estimate the null-distribution of complex statistics, an approach referred to as parametric bootstrapping, and are also used to test the quality of phylogenetic reconstruction programs. It has often been… CONTINUE READING
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Inferring Phylogenies

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