Non-homogeneous extracellular resistivity affects the current-source density profiles of up–down state oscillations

@article{Bazhenov2011NonhomogeneousER,
  title={Non-homogeneous extracellular resistivity affects the current-source density profiles of up–down state oscillations},
  author={Maxim Bazhenov and Peter Lonjers and Steven Skorheim and Claude B{\'e}dard and Alain Destexhe},
  journal={Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences},
  year={2011},
  volume={369},
  pages={3802 - 3819}
}
Rhythmic local field potential (LFP) oscillations observed during deep sleep are the result of synchronized electrical activities of large neuronal ensembles, which consist of alternating periods of activity and silence, termed ‘up’ and ‘down’ states, respectively. Current-source density (CSD) analysis indicates that the up states of these slow oscillations are associated with current sources in superficial cortical layers and sinks in deep layers, while the down states display the opposite… CONTINUE READING
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