Non-genetic mechanisms of diabetic nephropathy.

  title={Non-genetic mechanisms of diabetic nephropathy.},
  author={Qiuxia Han and Hanyu Zhu and Xiangmei Chen and Zhang-suo Liu},
  journal={Frontiers of medicine},
  volume={11 3},
Diabetic nephropathy (DN) is one of the most common microvascular complications in diabetes mellitus patients and is characterized by thickened glomerular basement membrane, increased extracellular matrix formation, and podocyte loss. These phenomena lead to proteinuria and altered glomerular filtration rate, that is, the rate initially increases but… CONTINUE READING