Non-gaussian analysis of diffusion-weighted MR imaging in head and neck squamous cell carcinoma: A feasibility study.

@article{Jansen2010NongaussianAO,
  title={Non-gaussian analysis of diffusion-weighted MR imaging in head and neck squamous cell carcinoma: A feasibility study.},
  author={Jacobus F. A. Jansen and Hilda E. Stambuk and Jason A Koutcher and Amita Shukla-Dave},
  journal={AJNR. American journal of neuroradiology},
  year={2010},
  volume={31 4},
  pages={
          741-8
        }
}
BACKGROUND AND PURPOSE Water in biological structures often displays non-Gaussian diffusion behavior. The objective of this study was to test the feasibility of non-Gaussian fitting by using the kurtosis model of the signal intensity decay curves obtained from DWI by using an extended range of b-values in studies of phantoms and HNSCC. MATERIALS AND METHODS Seventeen patients with HNSCC underwent DWI by using 6 b-factors (0, 50-1500 s/mm(2)) at 1.5T. Monoexponential (yielding ADC(mono)) and… CONTINUE READING

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