Non-frozen preservation protocols for mature mouse oocytes dramatically extend their developmental competence by reducing oxidative stress.

@article{Wang2014NonfrozenPP,
  title={Non-frozen preservation protocols for mature mouse oocytes dramatically extend their developmental competence by reducing oxidative stress.},
  author={Tian-Yang Wang and Qian Li and Qingbiao Li and Hong Li and Jiang Zhu and Wei Cui and G P Jiao and Jing-He Tan},
  journal={Molecular human reproduction},
  year={2014},
  volume={20 4},
  pages={318-29}
}
The objective of this study was to test whether aging induces oxidative stress (OS) during oocyte preservation at different temperatures and whether the oocyte competence can be extended by antioxidant supplementation. The increase in activation susceptibility was efficiently prevented when oocytes were preserved at 37°C for 9 h in HCZB medium with 10.27 mM… CONTINUE READING