Non-fibrillar beta-amyloid protein is associated with smooth muscle cells of vessel walls in Alzheimer disease.

@article{Frackowiak1994NonfibrillarBP,
  title={Non-fibrillar beta-amyloid protein is associated with smooth muscle cells of vessel walls in Alzheimer disease.},
  author={Janusz Frackowiak and A Zŏltowska and Henryk M. Wiśniewski},
  journal={Journal of neuropathology and experimental neurology},
  year={1994},
  volume={53 6},
  pages={637-45}
}
Meningeal blood vessels were studied in Alzheimer disease (AD) and control brain specimens obtained from autopsies within 16 hours after death. Serial sections were stained with thioflavine S and Congo red and immunostained for the presence of beta-amyloid precursor protein (beta PP) and beta-protein and for smooth muscle-specific proteins myosin, alpha-actin, and desmin. Isolated blood vessels were studied by immunoblotting for the presence of beta PP, fragments of beta PP, and beta-protein… CONTINUE READING
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