Non-equilibrium phase separation in mixtures of catalytically active particles: size dispersity and screening effects

  title={Non-equilibrium phase separation in mixtures of catalytically active particles: size dispersity and screening effects},
  author={Vincent Ouazan-Reboul and Jaime Agudo-Canalejo and Ramin Golestanian},
  journal={The European Physical Journal. E, Soft Matter},
Abstract Biomolecular condensates in cells are often rich in catalytically active enzymes. This is particularly true in the case of the large enzymatic complexes known as metabolons, which contain different enzymes that participate in the same catalytic pathway. One possible explanation for this self-organization is the combination of the catalytic activity of the enzymes and a chemotactic response to gradients of their substrate, which leads to a substrate-mediated effective interaction… 

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