Non-enterobacterial endotoxins stimulate human coronary artery but not venous endothelial cell activation via Toll-like receptor 2.

@article{Erridge2007NonenterobacterialES,
  title={Non-enterobacterial endotoxins stimulate human coronary artery but not venous endothelial cell activation via Toll-like receptor 2.},
  author={Clett Erridge and Corinne M. Spickett and David John Webb},
  journal={Cardiovascular research},
  year={2007},
  volume={73 1},
  pages={
          181-9
        }
}
OBJECTIVE To determine whether non-enterobacterial endotoxins, which are likely to constitute the majority of the circulating endotoxin pool, may stimulate coronary artery endothelial cell activation. METHODS AND RESULTS Interleukin-8 secretion, monocyte adhesion, and E-selectin expression were measured in human umbilical vein endothelial cells (HUVECs) and coronary artery endothelial cells (HCAECs) challenged in vitro with highly purified endotoxins of common host colonisers Escherichia coli… CONTINUE READING

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