Non-dopaminergic Treatments for Motor Control in Parkinson’s Disease

  title={Non-dopaminergic Treatments for Motor Control in Parkinson’s Disease},
  author={Susan H. Fox},
The pathological processes underlying Parkinson’s disease (PD) involve more than dopamine cell loss within the midbrain. These non-dopaminergic neurotransmitters include noradrenergic, serotonergic, glutamatergic, and cholinergic systems within cortical, brainstem and basal ganglia regions. Several non-dopaminergic treatments are now in clinical use to treat motor symptoms of PD, or are being evaluated as potential therapies. Agents for symptomatic monotherapy and as adjunct to dopaminergic… CONTINUE READING