Non-cytotoxic protection by human NK cells in mucosal secondary lymphoid tissues.

@article{Mnz2008NoncytotoxicPB,
  title={Non-cytotoxic protection by human NK cells in mucosal secondary lymphoid tissues.},
  author={Christian M{\"u}nz},
  journal={European journal of immunology},
  year={2008},
  volume={38 11},
  pages={2946-8}
}
Even though NK cells have been named for their spontaneous cytotoxicity, a large subpopulation of human NK cells primarily responds to activation with cytokine secretion and not killing. These CD56brightCD16(-) NK cells are abundant in secondary lymphoid tissues, can restrict pathogens that have breached mucosal barriers, and assist Th1 polarization during immune response priming. This exciting new aspect of NK-cell biology is discussed in this viewpoint. 

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Natural Killer CellsAnatomic structure is physical part ofLymphoid Tissue
Non - cytotoxic protection by human NK cells in mucosal secondary lymphoid tissues .
These CD56brightCD16(- ) NK cells are abundant in secondary lymphoid tissues , can restrict pathogens that have breached mucosal barriers , and assist Th1 polarization during immune response priming .
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