Non-crosslinking gold nanoprobes for detection of nucleic acid sequence-based amplification products.

@article{Mollasalehi2012NoncrosslinkingGN,
  title={Non-crosslinking gold nanoprobes for detection of nucleic acid sequence-based amplification products.},
  author={Hamidreza Mollasalehi and Razieh Yazdanparast},
  journal={Analytical biochemistry},
  year={2012},
  volume={425 2},
  pages={91-5}
}
Lack of an appropriate detection method for isothermal RNA amplification technique, known as nucleic acid sequence-based amplification (NASBA), is considered as a major defect for its vast applications. In that regard, novel detection methods as fast, specific, and sensitive as the gold nanoprobe detection technique are highly demanded and non-crosslinking gold nanoprobes are regarded as the ideal choice. In this study, we attempted to integrate these two techniques (RNA amplification and… CONTINUE READING