Non-classical MHC-I human leukocyte antigen (HLA-G) in hepatotropic viral infections and in hepatocellular carcinoma.

@article{Catamo2014NonclassicalMH,
  title={Non-classical MHC-I human leukocyte antigen (HLA-G) in hepatotropic viral infections and in hepatocellular carcinoma.},
  author={Eulalia Catamo and Luisa Zupin and Sergio Crovella and F Celsi and Ludovica Segat},
  journal={Human immunology},
  year={2014},
  volume={75 12},
  pages={1225-31}
}
The human leukocyte antigen (HLA)-G is a "nonclassical" major histocompatibility complex (MHC) class Ib gene, located at chromosome 6, in the 6p21.3 region. The HLA-G presents immunomodulatory functions essential in pregnancy for the tolerance of the semi-allogenic fetus, but an abnormal expression of HLA-G has been observed in numerous pathological… CONTINUE READING