Non-canonical roles of Bcl-2 and Bcl-xL proteins: relevance of BH4 domain.

Abstract

Bcl-2 protein family is constituted by multidomain members originally identified as modulators of programmed cell death and whose expression is frequently misbalanced in cancer cells. The lead member Bcl-2 and its homologue Bcl-xL proteins are characterized by the presence of all four conserved BH domain and exert their antiapoptotic role mainly through the… (More)
DOI: 10.1093/carcin/bgx016

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Cite this paper

@article{Gabellini2017NoncanonicalRO, title={Non-canonical roles of Bcl-2 and Bcl-xL proteins: relevance of BH4 domain.}, author={Chiara Gabellini and Daniela Trisciuoglio and Donatella del Bufalo}, journal={Carcinogenesis}, year={2017}, volume={38 6}, pages={579-587} }