Corpus ID: 26951825

Non-antioxidant molecular functions of alpha-tocopherol (vitamin E).

@article{Azzi2002NonantioxidantMF,
  title={Non-antioxidant molecular functions of alpha-tocopherol (vitamin E).},
  author={A. Azzi and R. Ricciarelli and J. Zingg},
  journal={FEBS letters},
  year={2002},
  volume={519 1-3},
  pages={
          8-10
        }
}
alpha-Tocopherol (the major vitamin E component) regulates key cellular events by mechanisms unrelated with its antioxidant function. Inhibition of protein kinase C (PKC) activity and vascular smooth muscle cell growth by alpha-tocopherol was first described by our group. Later, alpha-tocopherol was shown to inhibit PKC in various cell types with consequent inhibition of aggregation in platelets, of nitric oxide production in endothelial cells and of superoxide production in neutrophils and… Expand
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