Non-alcoholic steatohepatitis in children.

  title={Non-alcoholic steatohepatitis in children.},
  author={Eve A. Roberts},
  journal={Clinics in liver disease},
  volume={11 1},
  pages={155-72, x}
Non-alcoholic steatohepatitis (NASH) is an important liver disease in children; it can cause cirrhosis in children. The disease mechanism involves hepatic insulin resistance with hyperinsulinemia and changes in certain adipocytokines and inflammatory mediators. The differential diagnosis of childhood NASH includes metabolic disorders, drug hepatotoxicity, and alcoholic hepatitis in adolescent patients. The histologic features in childhood NASH often differ from those in adults who have NASH… CONTINUE READING