Non-alcoholic steatohepatitis: review of a growing medical problem.

  title={Non-alcoholic steatohepatitis: review of a growing medical problem.},
  author={K. Te Sligte and I. Bourass and J. P. Sels and Ann Driessen and R. W. Stockbrugger and G. H. Koek},
  journal={European journal of internal medicine},
  volume={15 1},
Non-alcoholic steatohepatitis (NASH) is a metabolic liver disorder that is seen in 2-6% of the general population. It manifests itself by elevated liver enzymes, frequently without symptoms. The histological findings include steatosis, inflammation, fibrosis, and cirrhosis. Three case reports are presented to illustrate features of NASH. A two-hit model has been proposed in the pathogenesis of NASH. The first hit is hepatic steatosis. A hypercaloric diet with high levels of carbohydrates and… CONTINUE READING


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