Non-alcoholic steatohepatitis: emerging molecular targets and therapeutic strategies

  title={Non-alcoholic steatohepatitis: emerging molecular targets and therapeutic strategies},
  author={Giovanni Musso and Maurizio Cassader and Roberto Gambino},
  journal={Nature Reviews Drug Discovery},
Non-alcoholic fatty liver disease — the most common chronic liver disease — encompasses a histological spectrum ranging from simple steatosis to non-alcoholic steatohepatitis (NASH). Over the next decade, NASH is projected to be the most common indication for liver transplantation. The absence of an effective pharmacological therapy for NASH is a major incentive for research into novel therapeutic approaches for this condition. The current focus areas for research include the modulation of… CONTINUE READING
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