Non-alcoholic fatty liver disease as a risk factor for hepatocellular carcinoma: mechanisms and implications

@article{Stickel2010NonalcoholicFL,
  title={Non-alcoholic fatty liver disease as a risk factor for hepatocellular carcinoma: mechanisms and implications},
  author={Felix Stickel and Claus Hellerbrand},
  journal={Gut},
  year={2010},
  volume={59},
  pages={1303 - 1307}
}
The pathophysiological significance of hepatic lipid accumulation in the absence of significant alcohol consumption is increasingly recognised. Thus, non-alcoholic fatty liver disease (NAFLD) is now considered the most common cause of liver enzyme elevation in Western countries.1 It is regarded as the hepatic manifestation of the metabolic syndrome (MS), characterised by central obesity and insulin resistance (IR), and resulting diabetes type 2, dyslipidaemia and hypertension.2 NAFLD… 
Hepatocellular carcinoma in non-alcoholic fatty liver disease: an emerging menace.
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  • G. Baffy
  • Medicine, Biology
    Journal of clinical and translational hepatology
  • 2013
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TLDR
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