Non-alcoholic fatty liver disease and its relationship with cardiovascular disease and other extrahepatic diseases.

@article{Adams2017NonalcoholicFL,
  title={Non-alcoholic fatty liver disease and its relationship with cardiovascular disease and other extrahepatic diseases.},
  author={Leon Anton Adams and Quentin M Anstee and Herbert Tilg and Giovanni Targher},
  journal={Gut},
  year={2017},
  volume={66 6},
  pages={1138-1153}
}
Key physiological functions of the liver, including glucose and lipid metabolism, become disturbed in the setting of non-alcoholic fatty liver disease (NAFLD) and may be associated with a systemic inflammatory 'milieu' initiated in part by liver-secreted cytokines and molecules. Consequently, the pathophysiological effects of NAFLD extend beyond the liver with a large body of clinical evidence demonstrating NAFLD to be independently associated with both prevalent and incident cardiovascular… CONTINUE READING
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