Non-Steroidal Anti-Inflammatory Drugs as a Treatment for Alzheimer’s Disease: A Systematic Review and Meta-Analysis of Treatment Effect

  title={Non-Steroidal Anti-Inflammatory Drugs as a Treatment for Alzheimer’s Disease: A Systematic Review and Meta-Analysis of Treatment Effect},
  author={Marina Miguel-{\'A}lvarez and A. Santos-Lozano and F. Sanchis-Gomar and C. Fiuza-Luces and H. Pareja-Galeano and N. Garatachea and A. Lucia},
  journal={Drugs & Aging},
  • Marina Miguel-Álvarez, A. Santos-Lozano, +4 authors A. Lucia
  • Published 2015
  • Medicine
  • Drugs & Aging
  • IntroductionAlzheimer’s disease (AD) is the cause of more than two-thirds of all dementia cases. Although there is no effective treatment against this disorder, its association with neuroinflammation suggests that non-steroidal anti-inflammatory drugs (NSAIDs) might represent a potential therapeutic option.ObjectiveThe objective of this study was to evaluate the efficacy of NSAIDs in the treatment of AD using a meta-analysis approach.MethodsMEDLINE, Web of Science, Science Direct, and the… CONTINUE READING
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