Non-Markovian fluctuations in Markovian models of protein dynamics

@inproceedings{Dua2008NonMarkovianFI,
  title={Non-Markovian fluctuations in Markovian models of protein dynamics},
  author={Arti Dua and R. Adhikari},
  year={2008}
}
Recent experiments using fluorescence spectroscopy have been able to probe the dynamics of conformational fluctuations in proteins. The fluctuations are Gaussian but do not decay exponentially, and are therefore non-Markovian. We present a theory where non-Markovian fluctuation dynamics emerges naturally from the superposition of the Markovian fluctuations of the normal modes of the protein. A Rouse-like dynamics of the normal modes provides very good agreement with the experimentally measured… CONTINUE READING

Figures from this paper.

Citations

Publications citing this paper.

Continuous dissolution of structure during the unfolding of a small protein.

  • Proceedings of the National Academy of Sciences of the United States of America
  • 2009
VIEW 1 EXCERPT
CITES BACKGROUND