Non-LPS components of Chlamydia pneumoniae stimulate cytokine production through Toll-like receptor 2-dependent pathways.

@article{Netea2002NonLPSCO,
  title={Non-LPS components of Chlamydia pneumoniae stimulate cytokine production through Toll-like receptor 2-dependent pathways.},
  author={Mihai G Netea and Bart Jan Kullberg and Jochem M. D. Galama and Anton F. H. Stalenhoef and Charles Anthony Dinarello and Jos W M van der Meer},
  journal={European journal of immunology},
  year={2002},
  volume={32 4},
  pages={1188-95}
}
Recent studies suggest that infection with Chlamydia pneumoniae is associated with atherosclerosis, and that cytokines play an important role in the initiation and progression of Chlamydia-induced inflammation. When freshly isolated peripheral blood mononuclear cells (PBMC) were stimulated for 24 h with sonicated C. pneumoniae, significant amounts of the… CONTINUE READING