Non-Invasive Hemodynamic Assessment of Aortic Coarctation: Validation with In Vivo Measurements

  title={Non-Invasive Hemodynamic Assessment of Aortic Coarctation: Validation with In Vivo Measurements},
  author={Lucian Mihai Itu and Puneet Sharma and Kristof Ralovich and Viorel Mihalef and Razvan Ioan Ionasec and Allen Everett and Richard Ringel and Ali Kamen and Dorin Comaniciu},
  journal={Annals of Biomedical Engineering},
We propose a CFD-based approach for the non-invasive hemodynamic assessment of pre- and post-operative coarctation of aorta (CoA) patients. Under our approach, the pressure gradient across the coarctation is determined from computational modeling based on physiological principles, medical imaging data, and routine non-invasive clinical measurements. The main constituents of our approach are a reduced-order model for computing blood flow in patient-specific aortic geometries, a parameter… CONTINUE READING
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