Non-Hodgkin lymphoma in children and adolescents.

  title={Non-Hodgkin lymphoma in children and adolescents.},
  author={A. Reiter},
  journal={Klinische Padiatrie},
  volume={225 Suppl 1},
Until the 1970s, childhood non-Hodgkin lymphoma (NHL) was an almost incurable disease. Since then tremendous progress has been made. In this article the contributions of the Berlin-Frankfurt-Münster (BFM)-group clinical studies to the development of efficacious treatment for childhood and adolescent NHL will be described.From 1975 to 2001, 6 consecutive cooperative multicenter studies were conducted into which a total of 2 190 protocol patients were enrolled. The probability of event-free… CONTINUE READING