Non-Hertzian approach to analyzing mechanical properties of endothelial cells probed by atomic force microscopy.

@article{Costa2006NonHertzianAT,
  title={Non-Hertzian approach to analyzing mechanical properties of endothelial cells probed by atomic force microscopy.},
  author={Kevin D. Costa and Alan Sim and Frank C-P Yin},
  journal={Journal of biomechanical engineering},
  year={2006},
  volume={128 2},
  pages={176-84}
}
Detailed measurements of cell material properties are required for understanding how cells respond to their mechanical environment. Atomic force microscopy (AFM) is an increasingly popular measurement technique that uniquely combines subcellular mechanical testing with high-resolution imaging. However, the standard method of analyzing AFM indentation data is based on a simplified "Hertz" theory that requires unrealistic assumptions about cell indentation experiments. The objective of this study… CONTINUE READING
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