Non-Dipping Blood Pressure Profile in Narcolepsy with Cataplexy

  title={Non-Dipping Blood Pressure Profile in Narcolepsy with Cataplexy},
  author={Yves Dauvilliers and Isabelle Jaussent and Benjamin Krams and Sabine Scholz and St{\'e}phane Lado and Patrick L{\'e}vy and Jean Louis P{\'e}pin},
  booktitle={PloS one},
BACKGROUND Patients with narcolepsy-cataplexy (NC) mostly exhibit undetectable hypocretin levels. Hypocretin system is one of the key players in the complex interaction between sleep and the cardiovascular system. We tested the hypothesis that hypocretin deficiency affects cardiovascular risk factors by measuring nighttime and daytime ambulatory blood pressure (BP) and the night-to-day BP ratio as well as endothelial dysfunction by the digital pulse amplitude response in drug-free patients with… CONTINUE READING
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