Non-Coding RNAs in Castration-Resistant Prostate Cancer: Regulation of Androgen Receptor Signaling and Cancer Metabolism

@inproceedings{Shih2015NonCodingRI,
  title={Non-Coding RNAs in Castration-Resistant Prostate Cancer: Regulation of Androgen Receptor Signaling and Cancer Metabolism},
  author={Jing-Wen Shih and Ling-Yu Wang and Chiu-Lien Hung and Hsing-Jien Kung and C C Hsieh and Martin Pichler},
  booktitle={International journal of molecular sciences},
  year={2015}
}
Hormone-refractory prostate cancer frequently relapses from therapy and inevitably progresses to a bone-metastatic status with no cure. Understanding of the molecular mechanisms conferring resistance to androgen deprivation therapy has the potential to lead to the discovery of novel therapeutic targets for type of prostate cancer with poor prognosis. Progression to castration-resistant prostate cancer (CRPC) is characterized by aberrant androgen receptor (AR) expression and persistent AR… CONTINUE READING
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