Non-Angiogenic Functions of VEGF in Breast Cancer

@article{Mercurio2006NonAngiogenicFO,
  title={Non-Angiogenic Functions of VEGF in Breast Cancer},
  author={Arthur M. Mercurio and Elizabeth A. Lipscomb and Robin E Bachelder},
  journal={Journal of Mammary Gland Biology and Neoplasia},
  year={2006},
  volume={10},
  pages={283-290}
}
This review advances the hypothesis that the function of vascular endothelial growth factor (VEGF) in breast cancer is not limited to angiogenesis, and that VEGF signaling in breast carcinoma cells is important for the ability of these cells to evade apoptosis and progress towards invasive and metastatic disease. In other terms, VEGF signaling provides a selective advantage for the survival and dissemination of breast carcinoma cells that may be independent of angiogenesis. The key component of… 

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