Non-AUG-initiated internal translation of the L* protein of Theiler's virus and importance of this protein for viral persistence.

@article{Eyll2002NonAUGinitiatedIT,
  title={Non-AUG-initiated internal translation of the L* protein of Theiler's virus and importance of this protein for viral persistence.},
  author={Olivier van Eyll and Thomas Michiels},
  journal={Journal of virology},
  year={2002},
  volume={76 21},
  pages={
          10665-73
        }
}
Theiler's virus is a neurotropic murine picornavirus which, depending on the strain, causes either acute encephalitis or persistent demyelinating disease. Persistent strains of Theiler's virus (such as DA) produce an 18-kDa protein called L* from an open reading frame overlapping that encoding the viral polyprotein. Neurovirulent strains (such as GDVII) are thought not to produce the L* protein, as the alternative open reading frame of these strains starts with an ACG codon instead of an AUG… CONTINUE READING

Citations

Publications citing this paper.
SHOWING 1-10 OF 35 CITATIONS

References

Publications referenced by this paper.
SHOWING 1-10 OF 34 REFERENCES

Influence of the Theiler’s virus L* protein on macrophage infection, viral persistence, and neurovirulence

  • O. van Eyll, T. Michiels
  • J. Virol
  • 2000
Highly Influential
8 Excerpts

Similar Papers

Loading similar papers…