Non-AIDS related malignancies 13 years after the availability of combined antiretroviral therapy

Abstract

Results Among hematological malignancies other than nonHodgkin’s lymphoma and primary central nervous system lymphoma, we observed three cases of acute myelogenic leukaemia and 4 episodes of Hodgkin’s lymphoma. A greater number of solid tumors involved different organs and sites: laryngeal cancer (8 cases, with 6 episodes of papillomatous laryngeal cancer), rhinopharyngeal squamous carcinoma (4 cases), adenocarcinoma of the lung (6 cases), gastric adenocarcinoma (3 episodes), esophageal carcinoma (2 patients), prostate cancer (4 cases), bladder adnocarcinoma (3 episodes) pancreatic adenocarcinoma (2 cases), and squamos anal carcinoma (2 episodes). Some of these malignancies have been reported with extremely rare frequency until now (usually as single-case anecdotal reports), in particular before the cART era. The patient’s age ranged from 34 to 67 years, the mortality rate of these episodes was very elevated (over 80%), and occurred 3-41 months after diagnosis, despite appropriate surgical and/or cytotoxic chemotherapy and/or radiotherapy.

DOI: 10.1186/1742-4690-7-S1-P71

Cite this paper

@inproceedings{Manfredi2010NonAIDSRM, title={Non-AIDS related malignancies 13 years after the availability of combined antiretroviral therapy}, author={Roberto Manfredi}, booktitle={Retrovirology}, year={2010} }