Non–Small Cell Lung Cancer Radiogenomics Map Identifies Relationships between Molecular and Imaging Phenotypes with Prognostic Implications

@inproceedings{Zhou2018NonSmallCL,
  title={Non–Small Cell Lung Cancer Radiogenomics Map Identifies Relationships between Molecular and Imaging Phenotypes with Prognostic Implications},
  author={M Zhou and Ann N C Leung and Sebastian Echegaray and Andrew J. Gentles and Joseph B. Shrager and Kristin C. Jensen and Gerald J. Berry and Sylvia K Plevritis and Daniel L. Rubin and Sandy Napel and Olivier Gevaert},
  booktitle={Radiology},
  year={2018}
}
Purpose To create a radiogenomic map linking computed tomographic (CT) image features and gene expression profiles generated by RNA sequencing for patients with non-small cell lung cancer (NSCLC). Materials and Methods A cohort of 113 patients with NSCLC diagnosed between April 2008 and September 2014 who had preoperative CT data and tumor tissue available was studied. For each tumor, a thoracic radiologist recorded 87 semantic image features, selected to reflect radiologic characteristics of… CONTINUE READING

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