Nomegestrol Acetate/Estradiol
@article{Yang2012NomegestrolA, title={Nomegestrol Acetate/Estradiol}, author={L. Yang and G. Plosker}, journal={Drugs}, year={2012}, volume={72}, pages={1917-1928} }
Nomegestrol acetate/estradiol is a combined oral contraceptive with approval in many countries. This fixed-dose combination tablet contains nomegestrol acetate, a highly selective progestogen, and estradiol, a natural estrogen. It is the first monophasic combined oral contraceptive to contain estradiol, and is taken in 28-day cycles, consisting of 24 active therapy days with 4 placebo days (i.e. 24/4-day cycles).In two large, 1-year, randomized, open-label, multicentre, phase III trials in… CONTINUE READING
14 Citations
The Effect of Therapeutic and Supratherapeutic Oral Doses of Nomegestrol Acetate (NOMAC)/17β-Estradiol (E2) on QTcF Intervals in Healthy Women: Results from a Randomized, Double-Blind, Placebo- and Positive-Controlled Trial
- Medicine
- Clinical Drug Investigation
- 2014
- 2
Effect of oral contraceptives containing estradiol and nomegestrol acetate or ethinyl-estradiol and chlormadinone acetate on primary dysmenorrhea
- Medicine
- Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology
- 2015
- 8
- PDF
Pharmacokinetics, tissue distribution, and excretion of nomegestrol acetate in female rats
- Chemistry, Medicine
- European Journal of Drug Metabolism and Pharmacokinetics
- 2014
- 6
- Highly Influenced
- PDF
Prediction of nomegestrol acetate pharmacokinetics in healthy female adolescents and adults by whole-body physiology-based pharmacokinetic modelling and clinical validation.
- Medicine
- Contraception
- 2016
- 2
Isolation, synthesis, and cytotoxicity evaluation of two impurities in nomegestrol acetate
- Chemistry, Medicine
- Archiv der Pharmazie
- 2019
Combined hormonal influence of cyproterone acetate and nomegestrol acetate on meningioma: a case report
- Medicine
- Acta Neurochirurgica
- 2019
- 4
Spontaneous regression of meningiomas after interruption of nomegestrol acetate: a series of three patients
- Medicine
- Acta Neurochirurgica
- 2019
- 9
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